Queen of the Thrones™ Castor Oil Pack Compress - The Famous Less-Mess & Heat-Less” Reusable Castor Pack Compress Refill. Made From Organic Cotton & Eco-Friendly Materials (Castor Oil sold separately)

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Our promise to you is always to provide the best source of Castor Oil available in the marketplace that is free of contaminants based on third-party testing at the time of bottling. Reply Holmes GM, Browning KN, Babic T, Fortna SR, Coleman FH, Travagli RA. Vagal afferent fibres determine the oxytocin-induced modulation of gastric tone. J Physiol. 2013 Jun 15;591(12):3081-100. doi: 10.1113/jphysiol.2013.253732. Epub 2013 Apr 15. PMID: 23587885; PMCID: PMC3832121. Andrade IM, Andrade KM, Pisani MX, Silva-Lovato CH, de Souza RF, Paranhos Hde F. Trial of an experimental castor oil solution for cleaning dentures. Braz Dent J. 2014 Jan-Feb;25(1):43-7. doi: 10.1590/0103-6440201302327. PMID: 24789291. Silvagno F, Vernone A, Pescarmona GP. The Role of Glutathione in Protecting against the Severe Inflammatory Response Triggered by COVID-19. Antioxidants (Basel). 2020 Jul 16;9(7):624. doi: 10.3390/antiox9070624. PMID: 32708578; PMCID: PMC7402141. Boddu SH, Alsaab H, Umar S, Bonam SP, Gupta H, Ahmed S. Anti-inflammatory effects of a novel ricinoleic acid poloxamer gel system for transdermal delivery. Int J Pharm. 2015 Feb 1;479(1):207-11. doi: 10.1016/j.ijpharm.2014.12.051. Epub 2014 Dec 24. PMID: 25542985.

Jenkins RE, Tanner JA. The structure of the major protein of the human erythrocyte membrane. Characterization of the intact protein and major fragments. Biochem J. 1977 Jan 1;161(1):139-47 No Authors Listed. Final report on the safety assessment of Ricinus Communis (Castor) Seed Oil, Hydrogenated Castor Oil, Glyceryl Ricinoleate, Glyceryl Ricinoleate SE, Ricinoleic Acid, Potassium Ricinoleate, Sodium Ricinoleate, Zinc Ricinoleate, Cetyl Ricinoleate, Ricinoleate, Glycol Ricinoleate, Isopropyl Ricinoleate, Methyl Ricinoleate, and Octyldodecyl Ricinoleate. . Int J Toxicol. 2007;26 Suppl 3:31-77. Miller MA, Renn BN, Chu F, Torrence N. Sleepless in the hospital: A systematic review of non-pharmacological sleep interventions. Gen Hosp Psychiatry. 2019 Jul-Aug;59:58-66. doi: 10.1016/j.genhosppsych.2019.05.006. Epub 2019 May 24. PMID: 31170567; PMCID: PMC6620136.Castor Oil is actually a common ingredient in eye solutions that work as artificial tears because of its ability to help support lubrication and also keep moisture in the eye. What if I’m on medications, hormone replacement therapy, birth control pills, IUDs, or supplements?

Castor Oil is a unique vegetable oil derived from the castor bean. It contains 90% ricinoleic acid , a fatty acid structure strikingly similar to that of prostaglandin E1. In simple terms, it is a strong anti-inflammatory 4 agent in our body.Holm T, Brøgger-Jensen MR, Johnson L, Kessel L.Glutathione preservation during storage of rat lenses in opti-sol-GS and castor oil. PLoS One. 2013 Nov 19;8(11):e79620. Doi: 10.1371/journal.pone.0079620. eCollection 2013. PMID: 24260265. Vieira C et al. .Effect of ricinoleic acid in acute and subchronic experimental models of inflammation. Mediators Inflamm. 2000;9(5):223-8 PMID: 11200362 Walker SC1, Trotter PD2, Swaney WT2, Marshall A3, Mcglone FP4. C-tactile afferents: Cutaneous mediators of oxytocin release during affiliative tactile interactions? Neuropeptides. 2017 Aug;64:27-38. doi: 10.1016/j.npep.2017.01.001. Epub 2017 Jan 19. PMID: 28162847 It even had a leading role in the Biblical story of Jonah who sat under a towering Castor Oil Plan t for shade . The plant must have held some huge cultural significance for it to remain in the story for over 2000 years. Goto E1, Shimazaki J, Monden Y, Takano Y, Yagi Y, Shimmura S, Tsubota K. Low-concentration homogenized castor oil eye drops for noninflamed obstructive meibomian gland dysfunction.Ophthalmology. 2002 Nov;109(11):2030-5.

Boddu SH1, Alsaab H2, Umar S3, Bonam SP2, Gupta H2, Ahmed S3. Anti-inflammatory effects of a novel ricinoleic acid poloxamer gel system for transdermal delivery. Int J Pharm. 2015 Feb 1;479(1):207-11. doi: 10.1016/j.ijpharm.2014.12.051. Epub 2014 Dec 24. Löken LS, Wessberg J, Morrison I, McGlone F, Olausson H. Coding of pleasant touch by unmyelinated afferents in humans. Nat Neurosci. 2009 May;12(5):547-8. Epub 2009 Apr 12. PMID: 19363489.Processed this way, the Castor Beans are crushed, then a chemical solvent (usually hexane) is used to help extract the oil. While this may be more cost effective, adding hexane can compromise the quality of the oil. This is why high-quality, organic Castor Oil will always be hexane-free. Liver detox May help balance inflammation in the liver area and optimize blood flow, supporting the detoxification process. Mascolo N, Izzo AA, Autore G, Barbato F, Capasso F. Nitric oxide and castor oil-induced diarrhea. J Pharmacol Exp Ther. 1994 Jan;268(1):291-5. PMID: 8301570. But over time, Castor Oil’s uses started to expand. By the late 1800s, it played an important role in manufacturing as an effective lubricant , and scientists were revisiting the plant for its toxic elements that could be harnessed and used as chemical warfare. Since then ricin has had nefarious uses as a biological weapon.

So if you’re looking for a sleep solution tool that can help calm nervousness or anxiety and support your sleep, try a… PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 643684, Ricinoleic acid; [cited 2022 Mar. 31]. Prajna NV, Pillai MR, Manimegalai TK, Srinivasan M Use of Traditional Eye Medicines by corneal ulcer patients presenting to a hospital in South India.Indian J Ophthalmol. 1999 Mar;47(1):15-8. Marwat SK1, Rehman F2, Khan EA1, Baloch MS1, Sadiq M1, Ullah I1, Javaria S1, Shaheen S1. Review – Ricinus communis – Ethnomedicinal uses and pharmacological activities.Pak J Pharm Sci. 2017 Sep;30(5):1815-1827.

Bonini S1, Coassin M, Aronni S, Lambiase A. Vernal keratoconjunctivitis. Eye (Lond). 2004 Apr;18(4):345-51. Ricardo JW, Lipner SR. Utilizing a Sleep Mask to Reduce Patient Anxiety During Nail Surgery. Cutis. 2021 Jul;108(1):36.doi: 10.12788/cutis.0285. PMID: 34397356. Expeller pressing, also known as the “screw press” method, is a method that uses a machine that exerts intense friction and pressure to extract the oil. Unlike some other extraction processes, expeller pressing doesn’t involve the addition of heat .