I eat a pretty basic diet of lean animal protein, vegetables and fruits, olive and coconut oil, with occasional sprouted grain and cheddar cheese, 2-3 liters of water per day with LMNT electrolytes. My balance is pretty decent, just a bit more unsteady once in a while but my memory seems to have deteriorated. Thnk Gd not anywhere near K.S. but enough to concern me. When I first came across all this info on thiamine I started supplementing and the worst of my mental confusion, nausea, loss of appetite went away within a few days. I stopped the B1 because of gut pain and the symptoms increased again, I then restarted the B1 and they decreased again. (Unfortunately I had been supplementing for a bit before performing the test but intermittently) I am now using the Authia cream since I struggle with oral supplementation. I have noticed that I feel really tired after applying the cream for most of the day. I seem to remember reading that this would also suggest deficiency as otherwise supplementing would have no effect. Palpitations, random bouts of fatigue, frequent urination(pale), tinnitus that randomly spikes worse than ever, horrible memory issues, anxiety and feeling of getting a seizure sometimes after a heavy meal, bad concentraion, anxiety, bad mood, , low motivatio, exercise intolerance, trouble keeping up my weight. I am about 180 cm, and keep losing weight till I reach about 59, and than it stalls. Should one refrain from taking TTFD supplements in the evening. Are they known to interfere with sleep?

I would love to know what caused my health problems, but my tests have mostly been normal except for Graves’ disease. Even my genome looks okay, with no problems on the thiamine or cobalamin transporter genes. It makes me a bit uneasy to keep my B12 level so high, so I’d really like to understand why I need it.Any light you could shed on this would be greatly appreciated.. Thanking you in advance for your time and help. Continuing to take the Alithiamine, after a few weeks, my stools just became what I would call “perfect” bowel movements, consistently. I was astonished. I also tended to feel a bit more energy and have not really felt any “air hunger” to an extreme level in quite a while. I continued taking it for a few months at the same 1 capsule 50mg dose until then I stopped taking Alithiamine for a little while to see what would happen and I noticed a slight increase in “air hunger” and constipation after a week or so. So I started taking it again and I noticed the symptoms decreased again. I am looking for the possibility of being able to do the ETK test to confirm a diagnosis but it is difficult here, so it may not be possible. I tried to go up to 150mg a few days ago – with the last 50mg dose at dinner – but that seemed to correlate with an increase in anxiety and insomnia. I cannot say whether this connection is real, as it could be the normal vicissitudes of my anxiety – but it has been severe. Well, maybe the issue was that I didn’t eat enough fat when I took it? I eat 2 salmon fillets whenever I take the allithamine and it works great to help me absorb it.

As our son grew we worked to reduce the sugar in his diet, but were not sugar free. From 2012 to 2014 he was on this regimen of sugary drinks and foods, recommended by a scientist and the dysautonomia symptoms ramped up from that, I think. Thiamine is found in health food stores as thiamine hydrochloride and thiamine mononitrate. These are known as “salts” of thiamine. Like dietary thiamine, they require a protein transporter to get the vitamin into the cell. Their absorption used to be thought to be extremely limited, but megadoses are effective in some situations. The absorption of salts is therefore inferior to that of the thiamine derivatives discussed above. They are all so-called “open ring (thiazole)” forms of thiamine and represent the most useful way of getting big doses of thiamine into the cell. The reader should be aware that when we talk about big doses of a vitamin, it is being used as a drug. Although they can be used for simple vitamin deficiency, their medical use goes far beyond that because they can be effective sometimes when thiamine absorption is genetically compromised. We Need Your Help So my question is, does this sound like thiamine deficiency that started a long time ago to you? What would be your recommendations in this case in terms of taking the Alithiamine. Should I increase dose? Should I try to lower the dose? Should I be able to reach a point of not having to rely on the supplement in the future? I’m wondering if you’ve ever seen anyone who had symptoms like mine and if this can all just be chalked up to a b1 deficiency. That maybe I’ll be able to eat something other than meat in the future. http://www.biolab.co.uk/index.php/cmsid__biolab_test/Vitamin_B1_(Thiamine)_-_transketolase_activity

I really believe I am onto something here though. I have decided to try an active form of B1 and am not sure if I should go with Alltiamine or Coenzymated B-1? Do you have any suggestions? I researched online and believe God led me to several medical articles stating that Thiamine deficiency during the refeeding phase could cause renal tubular dysfunction resulting in electrolyte losses via the kidneys. So electrolyte values during the refeeding phase after fasting could be Refeeding Syndrome’s intracellular losses -OR- urinary losses from Thiamine Deficiency. I have been trying to build up my Mg for a year. I take B6 with it. I am getting the multivitamin, and I get around 200mg B1 salts?a day. I have taken Benfotiamine from time to time but I tend to return to commonly available B1. Prior to 2004 had anorexia (including binging and purging for 10 years or so) and severe depression.